| Saturday 2nd October 2010 | ||||
| Aviva Premiership | ||||
| London Irish | v | Leeds Carnegie | Madejski Stadium | (15:00) |
| Northampton | v | Exeter | Franklin's Gardens | (15:00) |
| Harlequins | v | Newcastle | The Stoop | (15:00) |
| Saturday 23rd October 2010 | ||||
| Aviva Premiership | ||||
| Leicester | v | Bath | Welford Road | (14:30) |
| Gloucester | v | Harlequins | Kingsholm | (15:00) |
| Exeter | v | London Irish | Sandy Park | (17:15) |
| Saturday 30th October 2010 | ||||
| Aviva Premiership | ||||
| Northampton | v | Newcastle | Franklin's Gardens | (14:30) |
| Saracens | v | Exeter | Vicarage Road | (15:00) |
| Gloucester | v | Leicester | Kingsholm | (17:30) |
