South Africa will be looking to rectify a tough loss to England this weekend against France.
After a humbling by Ireland, Italy will look to bounce back against Georgia.
Check out our preview on Scotland's matchup with Wales in the Doddie Weir Cup.
Make sure you know when, where and on which channel each of the games are taking place
Check out Simon Middleton's England squad for their upcoming Autumn matches.
Graeme Forbes and Kane Palma-Newport discuss whether a lower tackle height should be trialled.
Paul Williams and Alan Pearey discuss whether rugby needs an orange card in the game.
Michael Cheika has named his Australia squad for the upcoming Rugby Championship.
See the Pumas squad new coach Mario Ledesma has picked for the upcoming Rugby Championship
Take a look at the full squad the Springboks will use for the upcoming Rugby Championship here.